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Martin schalling professional address

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Curriculum vitae MARTIN SCHALLING

Professional address: Center for Molecular Medicine, L8:00

Karolinska Institutet at Karolinska University Hospital

17176 Stockholm, Sweden

Phone: +46 70 484 1230, email:

Relevant web-sites

- Head and founder of the Neurogenetics group, KI 1993-present

- Professor of Medical Genetics (Neurogenetics), KI 1999-present

- CMM steering group member 2008-present

- Head CMM leadership program 2005-present

- Visiting professor Dept of Psychiatry, USP, Brazil 2014-present

- Visiting professor at Dept of Psychiatry, UCSD 2002-2003

- Medical Advisor Neuroscience for SmithKline Beecham 1999-2000

- Associate prof. in Molecular Medicine, KI 1993-1999

- Swedish MRC position (fo-ass tjänst) 1992-1997

- EMBO postdoctoral fellow at MIT 1990-1992

- Graduate fellowship (doktorandtjänst) Swedish MRC 1987-1990


- MAL 5, Academic Leadership Tomorrow 2010-2011

- Karolinska Institutet Leadership program: ”Future Leaders of KI” 1996-1998

- Postdoctoral fellow with Professor David Housman, M.I.T. 1990-1993

- PhD in Molecular Neurobiology with Professor Tomas Hökfelt 1990

- MD degree from the Karolinska Institutet 1983

KI External Research Evaluation 2011:

- Outstanding (highest level)


Swedish Medical Research Council, university and foundation grants 600.000 USD per year (2004-2015). Other support for exploratory research 400.000 USD.

Publications and students

- 290 papers/manuscripts and 120 abstracts to meetings and conferences.

- H-index currently at 66 (GoogleScholar)

- More than 20 publications in journals with IF over 10 (including Nature, Nature Genetics, Cell, Nature Medicine etc). Total 17 000 citations with an average of 34 per paper.

- Supervisor of 20 PhD and 1 Lic students with dissertation 1996-2014

- Currently supervisor of 9 PhD students

- Supervised 14 Masters projects with reports (20P).

- Supervisor of 12 postdoctoral students 1995-2011, currently 3 active

- Graduate Thesis committee member or opponent for 23 PhD´s

  • Direct detection of expanded nucleotide repeats in the human genome

Martin Schalling, Thomas J Hudson, David E Housman, 1997/12/9, US 5695933

  • Nucleic acids and polypeptides for controlling food intake and/or body weight, Jeanette Elisabeth Johansen, Martin Schalling, 2001/2/8, US 09778844

Scholarships and Awards

- Invited visiting professor at UCSD 2002-2003

- Ireland Established Investigator Award (NARSAD) 1995

- "Young promising scientist"(a large scale 3 year MRC grant) 1993

- Alvarengas Award (best medical publication, Swedish Soc. Med.) 1993

- NARSAD Young Investigator Award (NARSAD, USA) 1992-1994

- Flormanska Award (Thesis of the year, Royal Swedish Academy Sci.) 1990

- EMBO scholar at MIT 1990-1992

- Fulbright scholar 1989
Professional engagements

- Chair Swedish Psychiatry Foundation 2014-

- Coordinator KI- Mayo Clinic collaborative platform 2011-

- CoChair, World Congress Psych Genetics 2009

- Editorial board, The Open Psychiatry Journal 2007-

- Editorial Board, Current Psychiatry Reviews 2004-

- Advisory Board Max Planch Institute of Psychiatry 2003-

- Editorial Board, Genes, Brain and Behavior 2001-2012

- Group leader at Center for Molecular Medicine, KI 1997-

- Steering Committe member for Swedish Twin registry 1995-

Selected publications

O81. Schalling, M., T. J. Hudson, K. H Buetow & D. E. Housman. (1993) Direct detection of novel expanded trinucleotide repeats in the human genome. Nature Genetics, vol 4, 135-139.

O82. Hinds, L. H., C. T. Ashley, J. S. Sutcliffe, D. L. Nelson, S. T. Warren, D. E. Housman & M. Schalling. (1993) Tissue specific expression of FMR-1 provides evidence for a functional role in fragile X syndrome. Nature Genetics, vol. 3 , 36-43.
O94. Schalling, M, M. Ekman, E. Kaaya, A. Linde, & P. Biberfelt (1995) A role for a new herpes virus (KSHV) in Kaposi's sarcoma. Nature Medicine, vol. 1, 707-708.
O95. Lönnkvist, F, P. Arner, L. Nordfors & M. Schalling (1995) Overexpression of the obese (ob) gene in adipose tissue of obese subjects. Nature Medicine vol 1, 950-953.
O133. Lindblad K, P-O. Nylander, C. Zander, QP. Yuan, L. Stahle, C. Engström, J. Balciuniene, U. Pettersson, T Breschel, M. McInnis, CA. Ross, R. Adolfsson and M. Schalling. (1998) Two commonly expanded CAG/CTG repeat loci: involvement in affective disorder? Molecular Psychiatry, vol 3, 405-410.
O164. Engert J.C., P. Berube, J. Mercier, C. Dore, P. Lepage, B. Ge, J.P. Bouchard, J. Mathieu, S. B. Melancon, M. Schalling, E. Lander, K. Morgan, T. J. Hudson and A. Richter (2000) ARSACS, a spastic ataxia common in northeastern Quebec, is caused by mutations in a new gene encoding an 11.5 kb ORF. Nature Genetics, vol. 24, 120-125.
O206. Johansson C., M. Willeit, L. Aron, C. Smedh, J. Ekholm, T. Paunio, T. Kieseppä, D. Lichtermann, N. Praschak-Rieder, A. Neumeister, S. Kasper, L. Peltonen , R. Adolfsson, T. Partonen, and M. Schalling (2004) Seasonal affective disorder and the G protein -3-subunit C825T polymorphism. Biological Psychiatry, Vol 1;55, 317-319.
O240. CRY2 is Associated with Depression. Catharina Lavebratt 1*, Louise K. Sjöholm1, Pia Soronen2, Tiina Paunio2, Marquis P. Vawter3, William E. Bunney3, Rolf Adolfsson4, Yvonne Forsell5, Joseph C. Wu3, John R. Kelsoe6, Timo Partonen7, Martin Schalling, PlosOne. 2010, vol 5, e9407.
O248.Holtze M, P Saetre, S. Erhardt, L. Schwieler, T. Werge, T. Hansen, J Nielsen, S. Djurovic, I. Melle, O. A. Andreassen, H. Hall, L. Terenius, I. Agartz, G. Engberg, E. G. Jönsson, M. Schalling (2010) Kynurenine Monooxygenase (KMO) polymorphisms in Schizophrenia – An association study, Schizophr Research 2010 Oct 26.
O250. Hypothalamic mitochondrial dysfunction associated with anorexia in the anx/anx mouse. Lindfors C, Nilsson IA, Garcia-Roves PM, Zuberi AR, Karimi M, Donahue LR, Roopenian DC, Mulder J, Uhlén M, Ekström TJ, Davisson MT, Hökfelt TG, Schalling M, Johansen JE. Proc Natl Acad Sci U S A. 2011 Nov 1;108(44):18108-13. Epub 2011 Oct 24.
O252. Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. Sklar P, …., Schalling M, …., Purcell SM; Psychiatric GWAS Consortium Bipolar Disorder Working Group. Nature Genetics 2011 Sep 18;43(10):977-83.
O270. Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. International Consortium for Blood Pressure Genome-Wide Association Studies, Ehret GB, ……, Schalling M…….Kooner JS. Nature 2011 Sep 11;478 (7367):103-9.
O269. Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure.Wain LV et al. Nat Genetics 2011 Sep 11;43(10):1005-11. doi: 10.1038/ng.922
O272. Epigenetic aberrations in leukocytes of patients with schizophrenia: association of global DNA methylation with antipsychotic drug treatment and disease onset. Melas PA, Rogdaki M, Osby U, Schalling M, Lavebratt C, Ekström TJ. FASEB J. 2012Jun;26(6):2712-8, Mar 16. Epub.
O278. P2RX7: expression responds to sleep deprivation and associates with rapid cycling in bipolar disorder type 1. Backlund L, Lavebratt C, Frisén L, Nikamo P, Hukic Sudic D, Träskman-Bendz L, Landén M, Edman G, Vawter MP, Ösby U, Schalling M. PLoS One. 2012;7(8):e43057. doi: 10.1371/journal.pone.0043057. Epub 2012 Aug 28.
O284. Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. Cross-Disorder Group of the Psychiatric Genomics ConsortiumSmoller JWCraddock NKendler K, , Neale BMNurnberger JIRipke SSantangelo S,Sullivan PF. …., Schalling M, ….., Kendler K. Lancet. 2013 Apr 20;381(9875):1371-9. doi: 10.1016/S0140-6736(12)62129-1. Epub 2013 Feb 28.
O288. Allelic differences between Europeans and Chinese for CREB1 SNPs and their implications in gene expression regulation, hippocampal structure and function, and bipolar disorder susceptibility. Li M, Luo XJ, Rietschel M, Lewis CM, Mattheisen M, Müller-Myhsok B, Jamain S, Leboyer M, Landén M, Thompson PM, Cichon S, Nöthen MM, Schulze TG, Sullivan PF, Bergen SE, Donohoe G, Morris DW, Hargreaves A, Gill M, Corvin A, Hultman C, Toga AW, Shi L, Lin Q, Shi H, Gan L, Meyer-Lindenberg A, Czamara D, Henry C, Etain B, Bis JC, Ikram MA, Fornage M, Debette S, Launer LJ, Seshadri S, Erk S, Walter H, Heinz A, Bellivier F, Stein JL, Medland SE, Arias Vasquez A, Hibar DP, Franke B, Martin NG, Wright MJ; MooDS Bipolar Consortium, Strohmaier J, Breuer R, Meier S, Mühleisen TW, Degenhardt FA, Hoffmann P, Herms S, Schwarz M, Vedder H, Kammerer-Ciernioch J, Reif A, Sasse J, Bauer M, Zwick S, Hautzinger M, Wright A, Mitchell PB, Fullerton JM, Schofield PR, Montgomery GW, Martin NG, Czerski PM, Hauser J, Schumacher J, Maier W, Propping P; The Swedish Bipolar Study Group, Backlund L, Frisén L, Lavebratt C, Schalling M, Osby U; The Alzheimer’s Disease Neuroimaging Initiative; ENIGMA Consortium; CHARGE Consortium, Su B. Molecular Psychiatry. 2013 Apr 9. doi: 10.1038/mp.2013.37
O289. All SNPs are not created equal: genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPs. Schork AJ, Thompson WK, Pham P, Torkamani A, Roddey JC, Sullivan PF, Kelsoe JR, O'Donovan MC, Furberg H; Tobacco and Genetics Consortium; Bipolar Disorder Psychiatric Genomics Consortium; Schizophrenia Psychiatric Genomics Consortium, Schork NJ, Andreassen OA, Dale AM. PLoS Genetics 2013 Apr;9(4):e1003449. doi: 10.1371/journal.pgen.1003449. Epub 2013 Apr 25
O290. Long-term lithium treatment in bipolar disorder is associated with longer leukocyte telomeres. Martinsson L, Wei Y, Xu D, Melas PA, Mathé AA, Schalling M, Lavebratt C, Backlund L. Translational Psychiatry. 2013 May 21;3:e261. doi: 10.1038/tp.2013.37.
O292. Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Cross-Disorder Group of the Psychiatric Genomics Consortium, Lee SH, …, Schalling M, …. Wray NR. Nature Genetics 2013 Aug 11. doi: 10.1038/ng.2711. [Epub ahead of print]
O283. The KMO allele encoding Arg452 is associated with psychotic features in bipolar disorder type 1, and with increased CSF KYNA level and KMO expression. C. Lavebratt, S. Olsson, L. Backlund, L. Frisén, C. Sellgren, L. Priebe, P. Nikamo, L. Träskman-Bendz, S. Cichon, M.P. Vawter, U. Ösby, G. Engberg, Mikael Landén, S. Erhardt, M. Schalling. Molecular Psychiatry 2013, March 5, Epub.

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