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Expertise Statement


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Dr. Shengbo Cao

PhD


Professor in Veterinary Medicine

Vice dean of College of Veterinary Medicine



Expertise Statement


Teaching Duties

  • Animal infectious disease

Research Interests

  • Interaction between Japanese Encephalitis Virus (JEV) and host cells

  • Signal pathway of inflammatory reaction in CNS during JEV infection

  • Vaccine and diagnosis methods development for animal infectious diseases

Professional Memberships

  • Fellow of the State Key Laboratory of Agricultural Microbiology

Other Roles


  • The reviewer of Molecular Medicine、Vaccine、Future Virology、J Clinic Immune、Virus Research、Pakistan VET J、Chinese Veterinary Science

Education & Working Experience


Education:

Address Wuhan, Hubei, 430070, P.R China

Major Veterinary Medicine

Degree/Diploma Doctor

From: Month/Year To: Month/Year 09/2002 to 06/2005



  • School Name Huazhong Agricultural University

Address Wuhan, Hubei, 430070, P.R China

Major Veterinary Medicine

Degree/Diploma Master

From: Month/Year To: Month/Year 09/1999 to 06/2002



  • School Name Huazhong Agricultural University

Address Wuhan, Hubei, 430070, P.R China

Major Veterinary Medicine

Degree/Diploma Bachelor

From: Month/Year To: Month/Year 09/1994 to 06/1998


Working Experience


  • Employer Huazhong Agricultural University

Employer Address Wuhan, Hubei, 430070, P.R China

From: Month/Year To: Month/Year 01/2012 to now

Your Position Title Professor


  • Employer Huazhong Agricultural University

Employer Address Wuhan, Hubei, 430070, P.R China

From: Month/Year To: Month/Year 05/2007 to 01/2012

Your Position Title Associate Professor


Employer Address 1960 East-west Road, Honolulu, HI

From(Month/Year To: Month/Year) 10/2006 to 05/2008

Supervisor Yuanan Lu

Your Position Title Junior Researcher



  • Employer Huazhong Agricultural University

Employer Address Wuhan, Hubei, 430070, P.R China

From: Month/Year To: Month/Year 07/2003 to 10/2006

Supervisor Huanchun Chen

Your Position Title Lecturer



  • Employer Huazhong Agricultural University

Employer Address Wuhan, Hubei, 430070, P.R China

From: Month/Year To: Month/Year 07/1998 to 06/2003

Supervisor Huanchun Chen

Your Position Title Assistant



Publications (* Corresponding author)

  1. Zhu B, Ye J, Lu P, Jiang R, Yang X, Fu ZF, Chen H, Cao S*. Induction of Antigen-Specific Immune Responses in Mice by Recombinant Baculovirus Expressing Premembrane and Envelope Proteins of West Nile Virus. Virol J. 2012, 16; 9:132(IF2010=2.55)(Corresponding author).

  2. Zheng Chen, Lin Shao, Jing Ye, Yongmao Li, Shaomei Huang, Huanchun Chen and Shengbo Cao*. Generation and characterization of the monoclonal antibodies against NS3 and NS5 proteins of Japanese encephalitis virus. Hybridoma. 2012, 31(2):137-41 (IF2010=0.45)

  3. Li Mei, Peng Wu, Jing Ye, Lin Shao, Shaomei Huang,Yaoming Li, Xiaohong Yang, Huanchun Chen and Shengbo Cao*. Development and Application of an Antigen Capture ELISA Assay for Diagnosis of Japanese encephalitis Virus in Swine,Human and Mosquito. Virology J. 2012, 9:4. (IF2010=2.55)

  4. Xiaohong Yang, Lidan Hou, Jing Ye, Qigai He, Shengbo Cao*. Detection of Porcine Circovirus Type 2 in Mosquitoes from Pig Farms by PCR. Pakestan Vet J.2012, 32(1):134-135 (IF2010=0.71)

  5. Fang Li, Li Mei, Yaoming Li, Kaihong Zhao, Huanchen Chen, Peng Wu, Yonggang Hu, Shengbo Cao*. Facile fabrication of magnetic gold electrode for magnetic beads-based electrochemical immunoassay: Application to the diagnosis of Japanese encephalitis virus. Biosens Bioelectron. 2011, 26: 4253–4256(IF2010=5.34)

  6. Cao S, Wu C, Yang Y, Sniderhan LF, Maggirwar SB, Dewhurst S and Lu Y . Lentiviral vector-mediated stable expression of sTNFR-Fc in human macrophage and neuronal cells as a potential therapy for neuroAIDS. Journal of Neuroinflammation.2011, 8:48(IF2010=5.79)

  7. Yang Yang, Jing Ye, Xiaohong Yang, Rong Jiang, Huanchun Chen, Shengbo Cao*. Japanese encephalitis virus infection induces changes of mRNA profile of mouse spleen and brain. Virology J, 2011, 8:80(IF2010=2.55).

  8. Li Y, Ye J, Yang XH, Xu M, Chen L, Liu X, Chen H, Cao S*. Infection of mouse bone marrow-derived dendritic cells by live attenuated Japanese encephalitis virus induces cells maturation and triggers T cells activation. Vaccine, 2011, 29:855-862(IF2010=3.57).

  9. Cao S, Li Y, Ye J, Yang XH, Chen L, Liu X, Chen H*. Japanese Encephalitic Virus wild strain infection suppresses dendritic cells maturation and function, and causes the expansion of regulatory T cells. Virology J, 2011, 26; 8(1):39(IF2010=2.55).

  10. Huang F, Cao S, Cui X, Xiong C, Wang M, Lu Y, Wang W, Ye J, Liu X. Efficient gene delivery into fish cells by an improved recombinant baculovirus. J Virol Methods. 2011, 173(2):294-9(IF2010=2.14)(Co-first author).

  11. Li Y, Hou L, Ye J, Liu X, Dan H, Jin M, Chen H, Cao S*. Development of a convenient immunochromatographic strip for the diagnosis of infection with Japanese encephalitis virus in swine. J Virol Methods. 2010, 168(1-2):51-6(IF2010=2.14).

  12. Cox C, Cao S, Lu Y. Enhanced detection and study of murine norovirus-1 using a more efficient microglial cell line. Virol J. 2009, 10; 6:196(IF=2.55).

  13. Li Y, Xu M, Chen L, Zhu J, Ye J, Liu X, Sun Y, Chen H, Cao S*. Evaluation of Murine Bone Marrow-Derived Dendritic cells Loaded with Inactivated Virus as a Vaccine against Japanese Encephalitis Virus. Vaccine, 2009, 27(43): 6004-6010(IF2010=3.57).

  14. Li Y, Ye J, Cao S*, Xiao S, Zhao Q, Liu X, Jin M, Chen H. Immunization with pseudotype baculovirus expressing envelope protein of Japanese encephalitis virus elicits protective immunity in mice. J. Gene Med. 2009, 11(1):57-65(IF2010=3.10).

  15. Cao, S.B, S. Maggirwar, Huanyu Dou at el. Lentivirus vector mediated transduction and stable expression of a soluble, decoy tumor necrosis factor alpha receptor in immortalized microglial cell lines. J. Neurovirology. 2007, 13(S1):71

  16. Sun M, Liu X, Cao S*, He Q, Zhou R, Ye J, Li Y, Chen H. Inhibition of porcine circovirus type 1 and type 2 production in PK-15 cells by small interfering RNAs targeting the Rep gene. Vet Microbiol. 2007, 20; 123(1-3):203-209(IF2010=3.26).

  17. Song Y, Jin M, Zhang S, Xu X, Xiao S, Cao S, Chen H. Generation and immunogenicity of a recombinant pseudorabies virus expressing cap protein of porcine circovirus type 2. Vet Microbiol. 2007, 31; 119(2-4):97-104(IF2010=3.26).

  18. Zhou H, Jin M, Yu Z, Xu X, Peng Y, Wu H, Liu J, Liu H, Cao S, Chen H. Effective small interfering RNAs targeting matrix and nucleocapsid protein gene inhibit influenza A virus replication in cells and mice. Antiviral Res. 2007, 76(2):186-193(IF2010=3.61).

  19. Liu X, Cao S*, Zhou R, Xu G, Xiao S, Yang Y, Sun M, Li Y, Chen H. Inhibition of Japanese encephalitis virus NS1 protein expression in cell by small interfering RNAs. Virus Genes. 2006, 33(1):69-75(IF2010=1.71).

  20. Ju C, Fan H, Tan Y, Liu Z, Xi X, Cao S, Wu B, Chen H. Immunogenicity of a recombinant pseudorabies virus expressing ORF1-ORF2 fusion protein of porcine circovirus type 2. Vet Microbiol. 2005, 30; 109(3-4):179-90(IF2010=3.26).

  21. S Cao, H. Chen, J. Zhao et al. Detection of Porcine Circovirus Type 2, Porcine Parvovirus and Porcine Pseudorabies Virus from Pigs with Postweaning Multisystemic Wasting Syndrome by Multiplex PCR. Veterinary Research Communications. 2005, 29(3): 263-269(IF2010=1.05).

Contact details


  • Dr. Shengbo Cao

  • Tel 027- 87618028

  • E-mail:sbcao@mail.hzau.edu.cn

sbcao@126.com

  • Laboratory website http://csb.hzau.edu.cn/§








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